Evidence For Platelet Rich Plasma (PRP) Treatment Within Musculoskeletal Pain and Injury

What is the Evidence for PRP treatment for Musculoskeletal Pain and Injury?

We know due to clinical success that PRP treatment for pain and injury has great results and is very safe. We are a clinic that basis our practice on 2 fundamental principles 1) evidence based practice and 2) clinical efficacy and safety.

Below we have listed some of the recent clinical trials for the treatment of PRP for pain and injury treatment: efficacy and safety. Please note it is very important to interpret clinical trials with a critical eye. The benefit of clinical practice means you can tailor treatment far more specific to the individual. Whereas clinical trials have set protocols for processing, treatment and follow up.

The effects of platelet-rich plasma injections in different stages of knee osteoarthritis. 2023.

PRP Injections are Equivalent to Corticosteroid Injections for Frozen Shoulder. However, appear to be safer and better long-term. A Systematic Review of Prospective Cohort Studies. 2023.

The Effect of PRP Augmentation of Arthroscopic Repairs of Shoulder Rotator Cuff Tears on Postoperative Clinical Scores and Retear Rates: A Systematic Review and Meta-Analysis. 2023.

Role of Joint Injections of Platelet-Rich Plasma PRP in Frozen Shoulder: A Systematic Review. 2023.

Evolution and Clinical Advances of Platelet-Rich Fibrin PRF in Musculoskeletal Regeneration. 2023.

Evidence for Utilisation of Injectable Biologic Augmentation in Primary Rotator Cuff Repair: A Systematic Review of Data From 2010 to 2022. 2023.

Evaluation of the effect of joint PRP and hyaluronic acid injections on cartilage thickness in chronic knee osteoarthritis. 2023.

Effects of PRP in Tear Size Reduction in Shoulder Rotator Cuff Tear of the Supraspinatus Tendon Compared to Corticosteroids Injection. 2023

Comparison of Various Modalities in the Treatment of Early Knee Osteoarthritis: An Unsolved Controversy. 2023.

Effectiveness of PRP and Prolotherapy in comparison to exercise therapy, and in comparison to each other. Thus in knee osteoarthritis. 2023.

Clinical Efficacy of Joint Injection with P-PRP Versus that of L-PRP in Treating Knee Cartilage Lesion: A Randomized Controlled Trial 2023.

PRP for Joint Injections: Preclinical and Clinical Evidence 2023.

Pure Platelet and Leukocyte-

PRP for Regenerative Medicine in Orthopedics Time and Preparation Dependent Release of Growth Factors and Effects on Joint Health: A Comparative Analysis. 2023.

PRP versus corticosteroid injections in the management of patients with rotator cuff disease: A review and analysis 2023.

The role of corticosteroid injections in treating plantar fasciitis, with a comparison to PRP. A systematic review and meta-analysis. 2023.

Autologous PRP Administration on the Intervertebral Disc in Low Back Pain Patients with Modic Type 1 Change: Report of Two Cases 2023.

Cost-utility analysis and benefit of PRP joint injections in compared to Plasma Rich in Growth Factors (PRGF), Hyaluronic Acid (HA) and ozone in knee osteoarthritis in Iran 2023.

Injection of Autologous Platelet-Rich Plasma PRP for Tennis Elbow (refractory, lateral epicondylitis). Dec 2022.

Plasma rich in growth factors (PRGF) versus cortisone injections for chronic rotator cuff injury: a prospective double-blind randomised controlled trial with 1-year of follow-up. 2023.

Joint Injection of Microfat and PRP in the Treatment of Wrist Osteoarthritis 2022.

Effects of recurrent joint cortisone injections for osteoarthritis at 3 months and beyond: review and analysis in comparison to other injectables like PRP and Hyaluronic acid. 2022

Combination of mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) in the treatment of knee osteoarthritis: a meta-analysis of randomised controlled trials 2022.

PRP Versus Stem Cell (Adipose) for Knee Osteoarthritis: A Randomised Controlled Trial. 2022.

Reconstruction of Chronic Proximal Hamstring Tear: A Novel Surgical Technique with Semitendinosus Tendon Assisted with Plasma Rich in Growth Factors (PRGF). 2022.

Adjunctive platelet-rich plasma and hyaluronic acid injection after arthroscopic debridement in Kellgren-Lawrence grade 3 and 4 knee osteoarthritis 2022.

Injection of PRP for tendinopathies: a systematic review and meta-analysis 2022.

PRP Injections as an Alternative to Surgery in Treating Patients With Medial Epicondylitis: A Systematic Review. 2022.

Are leukocyte-poor or multiple injections of PRP more effective than hyaluronic acid for osteoarthritis? A systematic review and meta-analysis of randomized controlled trials. 2022.

Effect of autologous PRP combined with HA on clinical efficacy and serum inflammatory factors in patients with knee osteoarthritis Dec 2022

Top 100 Most Cited Articles on PRP Use in Regenerative Medicine. ESSKA Orthobiologic Initiative 2022.

Comparative Efficacy of PRP and Dry Needling for Management of Trigger Points in Myofascial Pain Syndrome Patients: A Randomized Controlled Trial 2022.

PRP use in meniscus repair treatment: a systematic review and meta-analysis of clinical studies 2022.

Application Value of Total Knee Arthroplasty plus Platelet-Rich Plasma Therapy in Traumatic Arthritis of the Knee 2022.

Comparison of the Efficacy of PRP and Local Corticosteroid Injection in Periarthritis Shoulder: A Prospective, Randomized, Open, Blinded End-Point (PROBE) Study 2022.

The levels of growth factors and PF4 in PRP of professional athletes 2022.

Efficacy and safety of PRP in the treatment of carpal tunnel syndrome: meta-analysis of different injection treatments 2022.

PRP Relieves Joint Fluid-Inducing Synovial Injury through NF-κB Pathway and Mitochondrial Apoptosis in Human Synovial Fibroblast Cells 2022.

Platelet-rich plasma PRP, a biomaterial, for the treatment of anterior talofibular ligament in lateral ankle sprain. Dec 2022.

Can PRP enhance the effect of meniscus repair 2022.

Effects of Joint PRP Treatment on Cartilage Thickness, Clinical and Functional Outcomes in Knee Osteoarthritis (Dec 2022) This study supports the efficacy of PRP in the management of osteoarthritis knee by improvement in pain, joint stiffness, and activities of daily living, as well as aids in the repair and regeneration of articular cartilage.

PRP Injections Decrease the Need for Any Surgical Procedure for Chronic Epicondylitis (covers album in tennis, elbow) versus Conservative Treatment-A Comparative Study with Long-Term Follow-Up (Dec 2022).

PRP Treatment - Superior to Corticosteroid Injection for Rotator Cuff Disease Because of Improved Chance of Healing, Longer-Lasting Pain Relief, and No Detriment if Surgery Is Needed (Dec 2022).

Intradiscal PRP Injection for Disc Related Low Back Pain: A Clinical Trial 2022.

Platelet-rich plasma vs corticosteroid for treatment of rotator cuff tendinopathy:a Meta-analysis (Dec 2022).

Comparison of the short-term effectiveness of 5% dextrose water, PRP and corticosteroid injections for carpal tunnel syndrome: systematic review and analysis of trials (Dec 2022).

Efficacy of PRP injection in the treatment of frozen shoulder: A systematic review and meta-analysis (Nov 2022).

PRP use for hip and knee osteoarthritis in the United States 2022.

Comparison of Joint Hyaluronic Acid and PRP Injection in Knee Osteoarthritis: Do the Results Differ in Geriatric Patients? Observational Study (Dec2022).

Assessment of the effectiveness and satisfaction of PRP compared with hyaluronic acid in knee osteoarthritis at minimum 7-year follow-up (2022).

Analysis of PRP and corticosteroid injection for radiculopathy in operated or unoperated patients for lumbar disc herniation 2022.

Modifying Orthobiological PRP Therapies Are Imperative for the Advancement of Treatment Outcomes in Musculoskeletal Pathologies 2022.

Role of PRP in the Treatment of Frozen Shoulder (Adhesive Capsulitis): Cohort Study (Oct 2022).

Joint Leukocyte-Poor PRP Injections for Patients With Osteoarthritis of the Knee: A Three-Year Observational Retrospective Study (Oct 2022).

Study protocol for a randomised trial of PRP injection to prevent post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction (Oct 2022).

Comparison of clinical outcome, cartilage turnover, and inflammatory activity following either joint or a combination of joint with bone PRP injections in osteoarthritis knee (Oct 2022).

Basic Science of Autologous Orthobiologics: Part 1. Platelet-Rich Plasma 2023.

Intradiscal Leukocyte Rich Platelet Rich Plasma for Degenerative Disc Disease. 2023

Orthobiologic Treatment of Ligament Injuries 2023

Orthobiologic Interventions for Muscle Injuries 2023.

Clinical Rationale and Rehabilitation Guidelines for Post Biologic Therapy 2023.

Autologous PRP Injections Versus Shockwave Therapy for Plantar Fasciitis in Athletes and Nonathletes: Comparative Study With Minimum 2-Year Follow-Up Oct 2022.

The role of PRP joint injections in restoring articular cartilage of osteoarthritic knees. A review analysis (2022)

Efficacy of PRP injection in the treatment of frozen shoulder: A systematic review and meta-analysis Dec 2022.

PRP Treatment of Recurrent Flexor Tenosynovitis of Wrist Complicated with Carpal Tunnel Syndrome in a Patient with Type 2 Diabetes Mellitus: A Case Report 2022.

The efficacy of PRP in osseous foot and ankle pathology 2022.

PRP reduces the retear rate on shoulder rotator cuff. Review 2022.

Comparison of PRP Treatment and Partial Plantar Fasciotomy Surgery in Patients with Chronic Plantar Fasciitis 2022.

The role of PRP joint injections in restoring joint cartilage of osteoarthritic knees. A systematic review and meta-analysis 2022.

PRP and Platelet-Related Products in the Treatment of Radiculopathy (nerve root entrapment) A Systematic Review of the Literature 2022.

Leukocyte and L-PRP in Tendons: A Systematic Review and Meta-Analysis of in vivo/in vitro Studies 2022.

Double-Blind Randomised Controlled Trial Comparing PRP With Joint Corticosteroid Injections in Patients With Bilateral Knee Osteoarthritis 2022.

Differences in Synovial Cytokine Profile Associated with Long-Term Clinical Outcomes in Patients with Knee Osteoarthritis Undergoing Corrective Osteotomy with Platelet-Rich Plasma or Stromal Vascular Fraction Post-Treatments 2022.

This page will be monitored and updated frequently in regards to new studies and information.

For more advice or information, please do not hesitate to contact us direct visit our website at:

www.dynamicregenmedicine.co.uk / clinic@dynamicregenmedicine.co.uk / 01564330773