Comparative histological and immunohistochemical study on the effect of platelet rich plasma/minoxidil, alone or in combination, on hair growth in androgenic alopecia.
Many of us are often unsure what the best course of treatment is when suffering with hair loss, particularly in this case androgenetic alopecia (pattern hair loss). New evidence below is looking at the comparison between PRP treatment and minoxidil on hair growth in androgenetic alopecia, which is the most common form of hair loss.Comparative histological and immunohistochemical study on the effect of platelet rich plasma/minoxidil, alone or in combination, on hair growth in androgenic alopecia.Many of us are often unsure what the best course of treatment is when suffering with hair loss, particularly in this case androgenetic alopecia (pattern hair loss). New evidence below is looking at the comparison between PRP treatment and minoxidil on hair growth in androgenetic alopecia, which is the most common form of hair loss.
In this particular study, experimental androgenetic alopecia was induced And then tested and analysed. That
Groups III, IV, and V showed significant increase in mean thickness, mean numbers of total hair follicles and anagen hair follicles, and decrease in telogen hair follicles compared to AGA group. Group V showed the best results. AGA group showed perifollicular fibrosis and follicular streamers. They were absent in PRP group and group V. Significant decrease of Ki-67 positive cells in AGA. PRP and minoxidil groups showed a significant increase in number of Ki-67 positive cells compared to control and AGA groups. Group V showed the highest number of Ki-67 positive cells.
To conclude - PRP was more effective than minoxidil in treatment of experimentally induced AGA. Results also indicated that results were maintained over a longer period of time. The best results were obtained when PRP and minoxidil were administered together.
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