What is play the rich plasma (PRP)?
Platelet-rich plasma (PRP), is a very popular therapeutic treatment that is of equal value to stem cells therapy. although were slightly differently, it is a very favourable technique as it is very simple, straightforward and non-invasive come at the same time as being cost-effective and of course clinically effective. PRP treatment is currently one of the most promising therapies in regenerative medicine. It is increasingly being used in many different areas of medicine including aesthetic dermatology, orthopaedics, sports medicine and surgery.
So where did PRP therapy come from?
In 1882, the role of platelets in blood coagulation was discovered, as well as their involvement in thrombosis. It was also discovered that the vascular wall of vessels had an inhibitory effect on platelet adhesion. In the early 1940s, clinicians used embryonic “extracts” composed of growth factors and cytokines to promote and facilitate wound healing, as rapid and effective wound healing is crucial for the success of surgical procedures.
It has been fully demonstrated that bioactive molecules which is growth factors were released from platelets to repair damaged tissue, such as skin ulcers. One of the most frequently investigated subjects in this field is a combination of PRP and hyaluronic acid. Progress in medicine has led to rapid advances in platelet clinical application. In 1972, for the first time, Matras used platelets as sealants to establish blood homeostasis during surgical procedures.
In 1975 Oon and Hobbs were the first scientists to use PRP in reconstructive therapy. In 1987, PRP therapy was used in heart surgery as an autologous source of transfusion for the first time, thus limiting blood loss. In 1986, Knighton et al. were the first scientists who described platelet concentrate protocols for wound healing. Since then formulating and advancing the protocols in this technique has led to many more clinical applied applications, and since the late 1980s, PRP has been used in regenerative medicine. Apart from general and cardiac surgery, PRP also started to be implemented in dentistry, where it has been used to improve incorporation of dental implants and facilitate bone regeneration. The popularity has grown ever since.
Since 2000, several agents activating PRP have been used, for example, calcium chloride and bovine thrombin. More excitingly, and due to exciting advancements in clinical practice, PRP is used in orthopaedics musculoskeletal medicine. The results of the first in-depth study on the effects of growth factors on tendon tissue in humans were published in 2005. PRP treatment is now currently used to treat many degenerative disorders, tendons issues, ligaments, muscles, and cartilage, all for a stimulating repair and facilitating healing. Is it the same time as reducing inflammation and promoting functional capacity. due to success and increased clinical popularity, PRP is frequently used within sports medicine for the treatment of athletes and is now frequently used in clinical practice.
In 2009, an animal study confirming the original hypothesis that PRP concentrate improves the healing of musculoskeletal tissue was published. Many further investigations have also looked into the fascinating mechanisms of PRP in the skin rejuvenation and of course the fascinating field of hair restoration. Since earlier than 2010, PRP has been successfully applied in cosmetic dermatology and hair restoration. Following a PRP injection treatment, improvements have been shown to promote younger looking skin that displays improved hydration and tone. This works via the release of growth factors that stimulate collagen production, naturally. PRP is also used to improve hair growth. Furthermore, it has been proven that treatment with PRP prior and post to hair transplantation, enhanced hair growth and improved hair density. In addition, in 2009, studies demonstrate graft acceptance and survival can be improved by using a mix of PRP, which may produce enhanced effects, fire stimulating better survival and improved function. The most recent research results in dermatology have demonstrated PRP therapy produces a more marked reduction in acne scars.
As we can see from this very short review, PRP has been used extensively and is continuing to advance and promote very good results, naturally via practically no side-effects. this is appealing to most. what we know and understand is the body has a fantastic and fascinating capability to promote healing, repair and regeneration. In our blood contains fascinating specialise cells that have very specialised functions. If we can utilise the cells along with their specialised functions within clinical practice then we are amplifying and stimulating these mechanisms via minimal mechanical manipulation.
Are you interested to find out more about how PRP treatment may be able to help you?
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